Department of Microbiology, Pritzker School of Molecular Engineering, and the College
Mark Mimee’s research focuses on developing strategies to precisely engineer the activity and composition of the microbiota. By genetically manipulating commensal microbes, he seeks to create living devices that can serve as biosensors to probe the structure and function of the microbiome and as cell-based therapeutics for infectious and inflammatory disease. Additionally, he develops approaches to augment the natural properties of viruses that infect bacteria, called bacteriophages, to create novel therapies that combat antibiotic-resistant pathogens. His long-term vision is to implement these synthetic biology technologies to chart new basic and translational studies to exploit the microbiota for human health.
His work has been published in Science, Nature Biotechnology, and Cell Systems, and has also been widely covered in such international media as The Associated Press, BBC, Newsweek, CBC, and Wired.
Mimee’s interest in microbial life began in Montreal, Canada, where he completed his bachelor’s degree in microbiology and immunology at McGill University. Inspired by the nascent field of synthetic biology, he pursued studies at the Massachusetts Institute of Technology, completing his PhD in microbiology as a Howard Hughes Medical Institute International Student Fellow and a Qualcomm Innovation Fellow.