Department of Medicine and the College
Joshua Weinstein is a biophysicist and molecular technologist. He develops DNA-based technologies for high-throughput encoding and decoding of biological information with a view toward applications in biology and medicine. Recently, he invented DNA microscopy, an imaging modality that uses DNA rather than light as an imaging medium in order to generate detailed pictures of how genetic diversity distributes spatially across biological specimens.
His research lab develops new modalities of biological measurement, drawing from tools in molecular biology, physics, and applied mathematics. The group builds on the premise that technological mastery of DNA synthesis, manipulation, and sequence-readout over the past few decades provides fundamentally new opportunities to deepen understanding and command of the microscopic world.
Weinstein earned his PhD in biophysics from Stanford University, where he published the first global measurements of immune receptor sequence repertoires, using the zebrafish as a model organism. He completed his postdoctoral work at the Broad Institute of MIT and Harvard, where he was a Simons Fellow of the Life Sciences Research Foundation.