Department of Medicine
Jonathan Grinstein is a physician specializing in cardiovascular disease and advanced heart failure. He treats patients through the use of left ventricular assist devices (LVADs), long-term intravenous medications or continuous infusion pump medications, and heart transplantation.
Grinstein uses echocardiographic and computed tomography techniques to noninvasively monitor the pressure and volume inside the heart of individuals with implanted LVADs. These techniques allow cardiologists to analyze a patient’s response and make adjustments in real time. Grinstein has conducted research to develop a “smart” LVAD that intuitively adjusts its speed based on the physiological needs of the patient. He is also using computational fluid dynamics, a novel technology integrating engineering and physiology, to study flow through the LVAD to best match the LVAD pump to the patient with the aim of reducing complications.
Grinstein received his MD from the University of Chicago. He then joined Brigham and Women’s Hospital, associated with Harvard Medical School, for internship and residency training in internal medicine. He returned to the University of Chicago for a three-year fellowship in cardiology, followed by specialty training in advanced heart failure. He is the director of mechanical circulatory support at the University of Chicago Medicine and a member of the Alpha Omega Alpha Honor Medical Society and the Gold Humanism Honor Society.