Departments of Medicine and Pathology and the College
Eric Pamer studies the impact of the intestinal microbiota on resistance to Clostridium difficile, Klebsiella pneumoniae, and vancomycin-resistant Enterococcus faecium infections. His laboratory models infections that occur in patients receiving broad-spectrum antibiotics during cancer treatment and bone marrow transplantation. The genomic and metabolic diversity of commensal bacteria is being investigated to identify strains that provide disease resistance. The Pamer lab also investigates the role of inflammatory monocytes in defense against infection and the interaction between intestinal microbes and the mammalian immune system.
Pamer received his MD from Case Western Reserve University Medical School and completed clinical training in internal medicine and infectious diseases at the University of California San Diego Medical Center. He was a postdoctoral fellow at Scripps Research Institute in California and the University of Washington before establishing a laboratory focusing on immune responses to microbial infection at Yale University. In 2000 he moved his laboratory to Memorial Sloan Kettering Cancer Center in New York, where he was the chief of infectious diseases, head of the Division of Subspecialty Medicine, and director of the Center for Microbes, Inflammation, and Cancer. At the University of Chicago, he serves as the inaugural faculty director of the Duchossois Family Institute: Harnessing the Microbiome and Immunity for Human Health.