Department of Medicine
Alfredo Garcia is broadly interested in understanding how local environments affect neurophysiology at multiple levels of biological organization. Through the use of transgenic technologies, optogenetics, and electrophysiological approaches, he works to understand how blood gas homeostasis affects neurodevelopment, synaptic plasticity, and the coordination of information among neural networks. His laboratory is currently studying these concepts within brainstem networks responsible for cardio-respiratory control and in the hippocampus. This work has numerous implications for understanding the neural basis of autonomic and cognitive dysfunction found in clinical conditions ranging from opioid overdose to epilepsy and sleep disordered breathing.
He has authored several peer-reviewed studies, published in journals that include Nature, Nature Neuroscience, Proceedings of the National Academy of Science of the United States of America, the Journal of Neuroscience, and the Journal of Physiology. He is a member of the American Physiological Society and the Society for Neuroscience.
Garcia received his bachelor’s degree in biological science from the Ohio State University and his PhD in biomedical sciences from Wright State University, where he was a Porter Physiology Development Fellow. He then completed a postdoctoral fellowship at the University of Chicago in the Department of Organismal Biology and Anatomy. Most recently, he was a senior scientist at Seattle Children’s Research Institute’s Center for Integrative Brain Research.