The Henry G. Gale Distinguished Service Professor
Department of Chemistry, James Franck Institute, Institute for Biophysical Dynamics, and the College
The central theme of Andrei Tokmakoff’s research is molecular dynamics, the time-dependent changes to molecular structures in chemical and biological processes. His research group is recognized for studies of molecular dynamics in chemistry and biophysics using ultrafast two-dimensional infrared spectroscopy, including descriptions of water hydrogen-bonding dynamics and protein conformational dynamics. His group has developed two-dimensional infrared spectroscopy, which uses sequences of ultrashort pulses of infrared light to capture the motions of molecules. By plucking different bond vibrations of a molecule and understanding how they interact with one another, they can deduce transient structural information, and molecular movies of the process can be constructed.
He has co-authored numerous publications, including “Amide I Two- Dimensional Infrared Spectroscopy of Proteins,” and “Structural Rearrangements in Water Viewed through Two-Dimensional Infrared Spectroscopy.”
Tokmakoff earned his MS and PhD degrees in chemistry from Stanford University. His many awards and honors include the Alfred P. Sloan Research Fellowship, Coblentz Award, National Fresenius Award, and Ernest K. Plyler Prize for Molecular Spectroscopy.
Tokmakoff joined the University of Chicago faculty in 2013.