Department of Neurobiology, Grossman Institute for Neuroscience, Quantitative Biology, and Human Behavior, and the College
Mark Sheffield’s research expertise is in the area of systems neuroscience. His approach to understanding the neural underpinnings of memory brings together cutting-edge imaging techniques that allow visual cell identification of neurons involved in a particular memory and real-time measurements of cellular and subcellular activity over long periods in behaving mice, with techniques that allow the manipulation of activity of those neurons. Ultimately this approach is expected to reveal the features of neural function at the circuit, cellular, dendritic, and synaptic levels that allow for the formation, storage, and recall of memories.
Sheffield’s research has been published in Nature Neuroscience, Nature, and the Journal of Physiology. He was recently awarded a grant from the Whitehall Foundation.
He earned an MSci (first class) in neuroscience from the University of Nottingham in the United Kingdom and a PhD in neurobiology from Northwestern University. Most recently he was a postdoctoral fellow at Northwestern, where his research project involved two-photon imaging of place cells at sub-cellular resolution.