Department of Human Genetics and the College
John Novembre is a computational biologist whose research focuses on problems at the intersection of evolutionary and human genetics. His work addresses how patterns of genetic diversity among individuals can be used to uncover the genetic basis of complex phenotypes, such as heritable disease risk and adaptive traits; reveal patterns of population structure and evolutionary history; predict the genetic risk and ancestry of a single individual (“personalized genomics”); and illuminate evolutionary processes from a mechanistic, genetic level. A major portion of his research involves developing novel methods for analyzing population genetic data. Much of this work has focused on population structure, particularly spatial patterns, as well as ancestry-based analyses. He is also studying human population structure and evolution, and the translation of advances in population genetics to non-model organisms.
Novembre has co-authored publications appearing in Nature Genetics, Molecular Biology and Evolution, Molecular Ecology, and Genome Research. He is the recipient of an Alfred P. Sloan Research Fellowship and was honored as a Searle Scholar. He received a postdoctoral fellowship in bioinformatics from the National Science Foundation, as well as a predoctoral fellowship from the Howard Hughes Medical Institute.
Novembre holds a PhD in integrative biology, with an emphasis in computational biology and genomics, from the University of California, Berkeley.
Novembre joined the University of Chicago faculty in 2013.